What is ‘Fanconi Hope?
Fanconi Hope is a national charitable trust set up by parents of Fanconi Anaemia (FA) affected children and clinicians with an interest in FA, to fund a UK FA national registry and to promote research that might benefit FA-affected children.

What is Fanconi Anaemia?
FA is a rare genetic disorder that affects young children leading to bone marrow failure and bone marrow transplantation, with risk of leukaemia and subsequent head & neck cancers. Further information about FA can be found at www.fanconihope.org

Why should I be interested in Fanconi Anaemia?
Although FA only affects a small number of children/families in the UK, the genes concerned, i.e., the ‘Fanconi pathway’ are of great potential importance for all. The Fanconi pathway is an important mechanism for keeping our DNA healthy and preventing cancers. The Fanconi pathway is often responsible for a cancer’s resistance to chemotherapy drugs. Knowing how to manipulate the Fanconi pathway is likely to lead to better and more successful treatments for all cancers.


registered charity number 1126894